Up All Night An irreverent look at parenthood through the point of view of an acerbic working mother, along with her stay-at-home husband and opinionated parents. Details Casts Videos Galleries Posters Season Lists Title Up All Night Genres Comedy Family First Air Date 2011-09-14 Last Air Date 2013-01-10 Episode Runtime 00 Hours 22 Minutes Total Season(s) 2 Total Episode(s) on All Seasons 35 Runtime 22 Production Companies Broadway Video, Universal Media Studios Christina Applegate... Reagan Brinkley... Will Arnett... Chris Brinkley... Maya Rudolph... Ava Alexander... Luka Jones... Scott Chafin... Up All Night (TV Series 2011) - Trailer (Trailer) Original Size (1280x720) Original Size (1920x1080) Original Size (1536x2048) Original Size (500x750) Season 1 24 Episode(s) 2011-09-14 Season 2 11 Episode(s) 2012-09-20